That substance is 5-MEO-DMT (5-methoxy-N,N-dimethyltryptamine) - a psychedelic naturally occurring in a number of plants (including the fabled ayahuasca) and in one very special species of toad: The Sonoran Desert Toad (native to the US state of Arizona and the Mexican state of Sonora), also sometimes referred to as the Colorado River Toad.

Chiric Sanango is a strict but benevolent teacher for those willing to take on the truth.

Toloache is known as an herbal love brew in Mexico, but it has other benefits, too - and some serious side effects.